Details for gene set NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS I[GSEA]

Table: GSEA Results Summary

Dataset	Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB
Phenotype	phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS I
Enrichment Score (ES)	-0.66864115
Normalized Enrichment Score (NES)	-1.5295933
Nominal p-value	0.00625
FDR q-value	0.1352738
FWER p-Value	0.913

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PRMT5	6571 2817	277	1.725	0.0154	No
2	MTA2	23934 18250	334	1.600	0.0405	No
3	MBD3	19695	868	0.920	0.0279	No
4	RBBP7	10887 6366 10886	950	0.850	0.0385	No
5	NCOR1	5402	1004	0.803	0.0497	No
6	HDAC1	9081	1222	0.661	0.0496	No
7	BAX	17832	1302	0.620	0.0562	No
8	HDAC10	22165	1310	0.615	0.0667	No
9	HDAC6	24197	1338	0.603	0.0758	No
10	SRF	22961 1597	1447	0.548	0.0796	No
11	HDAC2	20055	1583	0.497	0.0811	No
12	SUMO1	5826 3943 10247	1708	0.452	0.0823	No
13	RANBP2	20019	1763	0.431	0.0870	No
14	SIN3A	5442	2058	0.325	0.0769	No
15	YWHAE	20776	2133	0.303	0.0782	No
16	ZFPM1	18439	2490	0.199	0.0625	No
17	HDAC3	4844	2552	0.185	0.0624	No
18	NR2C1	10215	2666	0.162	0.0592	No
19	MEF2C	3204 9378	2762	0.145	0.0566	No
20	XRCC6	2286 8991	2817	0.136	0.0561	No
21	SIRT3	17569 3713	3164	0.086	0.0389	No
22	GATA1	24196	3343	0.071	0.0305	No
23	MAX	21034	4042	0.036	-0.0065	No
24	GATA2	17370	4069	0.036	-0.0073	No
25	SAP30	18871	4117	0.034	-0.0092	No
26	SAP18	5406	4216	0.032	-0.0139	No
27	YY1	10371	4772	0.022	-0.0435	No
28	MBD2	23521	5025	0.018	-0.0568	No
29	FBXW11	20926	5928	0.011	-0.1053	No
30	MBD3L2	10638 19557	5980	0.011	-0.1078	No
31	BCOR	12934 2561	6416	0.009	-0.1312	No
32	HOXA10	17145 989	6759	0.008	-0.1495	No
33	SMAD7	23513	7342	0.006	-0.1808	No
34	XPO1	4172	8147	0.003	-0.2241	No
35	MYOD1	18237	8554	0.002	-0.2460	No
36	UBE2I	5819 5820	9396	0.000	-0.2914	No
37	FKBP3	21056	9999	-0.001	-0.3239	No
38	CAMK4	4473	10887	-0.004	-0.3717	No
39	FHL2	13966	11529	-0.005	-0.4062	No
40	TUBB2A	21493	11910	-0.007	-0.4266	No
41	TNF	23004	12661	-0.010	-0.4669	No
42	ANKRA2	21578	13364	-0.015	-0.5045	No
43	HIST1H1E	21520	13392	-0.015	-0.5057	No
44	FOXO3	19782 3402	13423	-0.015	-0.5071	No
45	ACSS2	12242 2684	14100	-0.023	-0.5432	No
46	ESR1	20097 4685	14182	-0.025	-0.5471	No
47	PRKACA	18549 3844	14320	-0.027	-0.5540	No
48	NCOR2	9835 16367	14515	-0.031	-0.5640	No
49	HSP90AA1	4883 4882 9131	14678	-0.036	-0.5721	No
50	RBBP4	5364	14955	-0.045	-0.5862	No
51	SIN3B	5443	14981	-0.046	-0.5867	No
52	TNFRSF1A	1181 10206	15227	-0.057	-0.5989	No
53	HDAC9	21084 2131	15539	-0.081	-0.6143	No
54	MEF2D	9379	15716	-0.097	-0.6221	No
55	YWHAB	14744	15786	-0.105	-0.6240	No
56	NR3C1	9043	15860	-0.114	-0.6259	No
57	PPARGC1A	16533	16024	-0.143	-0.6322	No
58	GNB1	15967	16221	-0.189	-0.6394	No
59	HDAC11	17356	16254	-0.196	-0.6377	No
60	RANGAP1	2180 22195	16328	-0.212	-0.6379	No
61	ADRBK1	23960	16530	-0.266	-0.6441	No
62	CHD4	8418 17281 4225	16588	-0.283	-0.6422	No
63	HDAC8	24090	16662	-0.303	-0.6408	No
64	RFXANK	5378	16734	-0.330	-0.6388	No
65	SIRT2	18318	17287	-0.539	-0.6592	Yes
66	GNG2	4790	17432	-0.617	-0.6561	Yes
67	SIRT1	19745	17477	-0.643	-0.6472	Yes
68	SIRT7	9923	17563	-0.694	-0.6395	Yes
69	RELA	23783	17583	-0.705	-0.6282	Yes
70	CREBBP	22682 8783	17641	-0.746	-0.6181	Yes
71	NFKB1	15160	17682	-0.778	-0.6066	Yes
72	HIST1H4B	6820	17854	-0.907	-0.5999	Yes
73	NFKBIA	21065	18048	-1.142	-0.5902	Yes
74	ACSS1	12729	18096	-1.212	-0.5715	Yes
75	HIST1H4D	11410	18178	-1.322	-0.5526	Yes
76	HDAC5	1480 20205	18194	-1.345	-0.5297	Yes
77	STAT3	5525 9906	18210	-1.378	-0.5063	Yes
78	HIST2H4A	15240	18213	-1.384	-0.4821	Yes
79	HIST1H4C	6643	18272	-1.523	-0.4584	Yes
80	HIST1H4J	11411	18310	-1.638	-0.4316	Yes
81	HIST1H4I	6645	18313	-1.645	-0.4028	Yes
82	HIST1H4F	6644	18328	-1.691	-0.3739	Yes
83	HIST1H4A	11590	18396	-1.845	-0.3450	Yes
84	HIST1H4K	11412	18430	-1.967	-0.3122	Yes
85	CDKN1A	4511 8729	18439	-2.021	-0.2771	Yes
86	HIST1H4H	7618	18460	-2.146	-0.2405	Yes
87	HIST4H4	6747	18489	-2.351	-0.2007	Yes
88	TP53	20822	18549	-2.941	-0.1522	Yes
89	BCL6	22624	18554	-3.060	-0.0986	Yes
90	RAN	5356 9691	18611	-5.795	0.0003	Yes